Leah Estrogen

Leah Estrogen is the tritagonist of the 2001 live-action/animated film, Osmosis Jones, where she serves as Mayor Phlemming’s personal secretary and love interest later girlfriend to Osmosis Jones.

Why She Rocks

 * 1) She is hard-working and very serious who wants to do what's right, even if it gets her caught and almost killled.
 * 2) She has a great character design; she is a red blood cell, though her cytoplasm is dark purple, while her membrane is a lighter shade of purple.
 * 3) She is wonderfully animated with a wide range of emotions from worry, joy, shock and accompanied by the voice of singer Brandy Norwood.
 * 4) She is the only one who tries to talk sense into the unreasonable Mayor Phlemming, and is brave enough to confront him when his irresponsible ways cross the line.
 * 5) She may be aloof and unpleasant towards Ozzy, but she ultimately turns out to be a very good-hearted character, and even tries to talk some sense into Phlegmming.
 * 6) Though she plays a supporting role, she is the one who alerted the police of Thrax after he steals chromosomes from the Frank's hypothalamus, driving up Frank's body temperature and (nearly) killing him.
 * 7) She is incredibly well-written, always knowing what to say with a deadpan but serious attitude.

Bad Qualities

 * 1) Like many reviewers who critiqued the movie like the Nostalgic Critic, she lacks a clear personality.
 * 2) Leah does not appear in Ozzy & Drix, being replaced by a new character. This is presumably because Osmosis Jones and Drix had already moved away from Frank DeTorre's body.

Trivia

 * Her last name, Estrogen means a hormone in the female body.
 * Ozzy accidentally calls Leah Brandy, which was left in because the directors thought that the mistake was funny.