Pinky and The Brain (Animaniacs)

Pinky and the Brain are a duo of anthropomorphic mice and secondary characters from Animaniacs, they later received their own spinoff. Pinky is a silly, happy-go-lucky mouse and is an assistance to Brain, an intelligent mouse who wants to take over the world. They are voiced by Rob Paulsen and Maurice LaMarche respectively.

Overall

 * 1) They have a great chemistry/relationship with each other and make a perfect comedic duo.
 * 2) Out of all the wonderful characters from Animaniacs, they have received the most spin-offs like Pinky and the Brain and Pinky, Elmyra, and the Brain.
 * 3) Their designs are great.
 * 4) They have a very catchy theme song.
 * 5) They were so well received, that they returned on the 2020 reboot.

Pinky

 * 1) Just like Ed and Patrick Star, his stupidity is very charming and hilarious.
 * 2) He has a lot of funny quotes like "Narf!" and "Egad!".
 * 3) Despite being stupid, Pinky does show some sign of intelligence whenever he thinks Brain's plans are going to backfire.
 * 4) His laugh is very funny
 * 5) He usually contributes the funniest moments in the show. Mainly due to his quirky, hyperactive nature.
 * 6) He is very loyal and trusting towards Brain.
 * 7) Rob Paulsen does a wonderful job voicing Pinky.

The Brain

 * 1) Most of his plans on wanting to take over the world are very unique and creative.
 * 2) Despite wanting to take over the world, he cares deeply for Pinky, even though he doesn’t want to admit it.
 * 3) His personality is very charming since he is calm and cynical.
 * 4) He has an emotional backstory on why he wants to take over the world.
 * 5) After reading Pinky's list on A Pinky and the Brain Christmas, he orders everyone to have a merry Christmas rather than conquering the world.
 * 6) He also has great lines such as "Yes!" and "You pondering what I'm pondering?".
 * 7) His facial expressions whenever he gets angry are hilarious.
 * 8) Maurice LaMarche does an excellent job voicing him and making him sound a lot like Orson Welles.

Overall

 * 1) They were flawed on Pinky, Elmyra, and the Brain, especially Pinky.
 * 2) In Pinky, Elmyra, and the Brain, both of them have been reduced into huge punching bags all because of Elmyra Duff's non-stop abuse, even though the duo didn't deserve it.

Pinky

 * 1) He can be irritating at times.
 * 2) Because of his stupidity, he has also done some disgusting stuff as well (primarily because of potty humor such as belches/etc).

The Brain

 * 1) He can be a bit mean to Pinky such as whenever he hits him.